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‘25 ‘21 University of Houston ‘15 University of Texas at Austin jacobKmcpherson.com
Jacob K McPherson PharmD PhD









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Jacques Cornwell describes in Nature a seven-step framework to help bridge the gap from passively reading a research paper to actively analysing it. “Although there is no universal framework for pulling apart a dense primary paper, having a consistent method is crucial.” #Academicsky 🧪
A phase 3 trial reported in Nature Medicine shows weekly subcutaneous injections of survodutide, a glucagon receptor/GLP-1R dual agonist, lowered liver fat content and body weight in adults with obesity and at-risk metabolic dysfunction-associated steatotic liver disease (MASLD). #medsky 🧪
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Training a neural network to collate data from several sources provides a high-resolution view of how people are moving around the world go.nature.com/4omsyUl
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Induction of β-Defensin 1 (DEFB1) via synthetic mRNA reduces Cryptosporidium parvum infection in human intestinal cells ✅ Just Accepted 🔗 https://bit.ly/3PZzE4t
Nearly all systemic antifungal clinical trial sites in the US are metropolitan, with just 0.6% of rural residents living within 30 miles of a treatment trial site. ja.ma/4uB4a2L
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Further unraveling the association between HIV, immune suppression, and cancer survival ✅ Just Accepted 🔗 https://bit.ly/4vGiXKk
By sticking to a clear strategy when reading, I get much more out of the literature, says Jacques Cornwell.
go.nature.com
Seven steps for critically analysing research papers
As presented at the American Diabetes Association Meeting, in this phase 3 trial, weekly subcutaneous injections of survodutide, a glucagon receptor/GLP-1R dual agonist, lowered liver fat content and body weight compared to placebo in adults with obesity and at-risk metabolic dysfunction-associated steatotic liver disease (MASLD).
Survodutide in adults with obesity and metabolic dysfunction-associated steatotic liver disease: SYNCHRONIZE-MASLD, a randomized, double-blind, placebo-controlled phase 3 trial - Nature Medicine
go.nature.com
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Impact of Methicillin Resistance on Outcomes of Staphylococcus aureus Bacteremia at a U.S. Center, 2023–2024 ✅ Just Accepted https://bit.ly/4ek9UYC
Nature Portfolio
Nature Portfolio
Peptide injections are the hottest trend in wellness, but researchers say enthusiasm for these unregulated drugs has got ahead of the science. go.nature.com/4xrwSWf
📢Out now! Marta C. González, Yanyan Xu, and colleagues introduce neuroGravity, a model to reconstruct mobility networks in data-scarce regions. www.nature.com/articles/s43... #cssky 🔓 rdcu.be/fowww
Training a neural network to collate data from several sources provides a high-resolution view of how people are moving around the world.
go.nature.com
Artificial intelligence shines a light on hidden global migration flows
Among US veterans with #HeartFailure with reduced ejection fraction, fewer than one-quarter achieved quadruple guideline-directed medical therapy within 2.9 years, and medication copays were associated with lower rates of therapy achievement. ja.ma/3Qk1Tuv
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Nature
In a contemporary academic cohort of adults with Staphylococcus aureus bacteremia, methicillin resistance was associated with distinct epidemiologic charac
bit.ly
Impact of Methicillin Resistance on Outcomes of Staphylococcus aureus Bacteremia at a U.S. Center, 2023–2024
Nature - Peptide injections are the hottest trend in wellness. Researchers say enthusiasm for these unregulated drugs has got ahead of the science.
go.nature.com
JAMA Network Open
Is the peptide craze backed by science? The promise behind the hype
Nature
The Journal of Infectious Diseases
Nature Computational Science
Open Forum Infectious Diseases
JAMA Cardiology
This study presents neuroGravity—a model that merges physics with machine learning to reconstruct mobility networks in data-scarce regions. It provides crucial tools for equitable urban planning, reve...
www.nature.com
Transferable human mobility network reconstruction with neuroGravity - Nature Computational Science
Clinical Infectious Diseases