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Center of multi-disciplinary scientists at the University of Louisville striving to uncover the mysteries of the cardiovascular system. www.CenterforCardioMetabolicScience.org
Center For Cardiometabolic Science






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Latest from the Wysoczynski lab! In Experimental Hematology, Stephan et al. show that after MI, SiglecF⁺ neutrophils arise locally in the heart—not from immature cells, but from mature CD101⁺ neutrophils.
Several of the faculty and trainees from the center presented their latest cutting-edge cardiovascular research at last week's International Society for Heart Research-North American section meeting in Minnesota. It was a great meeting for all. #ISHRNAS2026 #cardiosky
Professor Guyton built his career on feedback control, so consider this our (slightly delayed) feedback: Dr. Helen Collins winning the 2026 Arthur C. Guyton Award is exactly the equilibrium the field should settle into. Congratulations, Helen! 🫀 #Cardiosky #Physiology
Huge congratulations to Dr. Benjamin Doelling (pictured) on defending his PhD today! His work shows that restoring cardiac carnosine levels in heart failure reduces chronic cardiac inflammation and rescues cardiac function. We are proud of you and your accomplishments.
Rounding out the CCS presentations, Dr. Helen Collins will present in the Women's Cardiovascular Health Session in the Nicollet D room at 8 am on June 3. Her presentation will discuss recent findings from the lab examining Remodeling in the Female Heart in response to Pathological Stress.
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For more information on the award, see: medicine.louisville.edu/news/univers...
This phenotype is driven by inflammatory cues (TGF-β/GM-CSF) and enhanced by G-CSF priming—highlighting tissue-driven immune heterogeneity. Way to go, Team. Check out the paper here: pubmed.ncbi.nlm.nih.gov/42019709/
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Center For Cardiometabolic Science
Center For Cardiometabolic Science
Center For Cardiometabolic Science
May 13, 2026 | What began as a focused effort to better understand the female heart has grown into a nationally recognized research program for Helen E. Collins, assistant professor of medicine at the...
medicine.louisville.edu
University of Louisville researcher receives national award for excellence in integrative physiology
Center For Cardiometabolic Science
Center For Cardiometabolic Science
Myocardial infarction (MI) triggers an immune response marked by rapid infiltration of neutrophils. Although once considered a uniform population, neutrophils display remarkable heterogeneity post-MI,...
pubmed.ncbi.nlm.nih.gov
SiglecF-expressing neutrophils differentiate from mature neutrophils locally in the heart after myocardial infarction - PubMed
Center For Cardiometabolic Science
Center For Cardiometabolic Science