Associate Professor at FSU studying spatial orientation, reference frame coordination, sleep, and learning & memory in healthy and diseased/disordered brain states.
Excited to finally see this out! unexpected findings (and null results) can end exciting. One hidden nugget is that early before significant aggregation 3xtg mice sleep more by many measure. should have an answer to poss why coming soon!
journals.sagepub.com/doi/abs/10.1...
Check out this fascinating article aging.jmir.org/2026/1/e79224
The oscillatory biology of sleep: Linkage to dementia | Science www.science.org/doi/10.1126/...
Relationship between locus coeruleus and slow‐wave sleep in aging and Alzheimer's disease - Falgàs - 2026 - Alzheimer's & Dementia - Wiley Online Library alz-journals.onlinelibrary.wiley.com/doi/10.1002/...
Posterior parietal cortex oscillatory activity reflects persistent spatial memory impairments induced by early hippocampal amyloidosis in male mice - Djebari - The Journal of Physiology - Wiley Online Library physoc.onlinelibrary.wiley.com/doi/full/10....
Empathy and prosocial behavior powered by orexin-driven theta oscillations | Science www.science.org/doi/10.1126/...
Excited to share our latest story! We found disentangled memory representations in the hippocampus that generalized across time and environments, despite the seemingly random drift and remapping of single cells. This code enabled the transfer of prior knowledge to solve new tasks
We usually assume 🐜 ants 🐜 learn views when facing their goal, but our data shows that it is not necessarily the case!
We combined field experiments with a biologically constrained model to show how a two-stage neural circuit (MB -> CX) could allow this:
www.nature.com/articles/s41...
Dual orexin receptor antagonism with lemborexant enhances #microglial clearance of β-#amyloid in mice
Ashish Sharma, Emiko Segawa, Xiaoying Chen...Erik S. Musiek @washumedicine.bsky.social #Sleep #AlzheimersDisease
link.springer.com/article/10.1...
Background: Spatial navigation relies on egocentric and allocentric frames of reference, with the latter critically impaired in Alzheimer disease (AD) due to hippocampal involvement. Recent evidence s...
During wakefulness, neuromodulators operate largely independently to support behavior and cognition. By contrast, sleep reorganizes their activity into a coordinated brain rhythm. During sleep, the ma...
This review offers a personal and historical perspective on spatial representations of the local environment in hippocampal regions CA1 and subiculum, as derived from extracellular electrophysiologic...
Empathy measured through observational fear in rodents has been associated with increased theta oscillations in the anterior cingulate cortex (ACC). However, upstream circuit mechanisms modulating the...
Background Sleep is an essential component of memory consolidation and waste clearance, including pathology associated with Alzheimer's disease (AD). Facil...
journals.sagepub.com
INTRODUCTION Sleep disruption, particularly loss of slow-wave sleep (SWS), is common in Alzheimer's disease (AD), but its neurobiological underpinnings remain unclear. We investigated whether locus ...
