A membrane homeostatic response to lipid overload coordinates fatty acid metabolism www.biorxiv.org/content/10.6...
Differential spatial regulation and activation of integrin nanoclusters inside focal adhesions www.biorxiv.org/content/10.1...
The centriculum, a membrane reticulum that surrounds C. elegans centrosomes, may serve as a microtubule filter journals.biologists.com/jcs/article/...
Mechanism of lipid transfer by bridge-like protein VPS13A and the scramblase XK: Cell www.cell.com/cell/fulltex...
Drp1-driven fragmentation of scleral mitochondria promotes myopia development | PNAS www.pnas.org/doi/10.1073/...
De novo E-cadherin/catenin complex formation controls basal epithelial mechanics and force transmission for apoptotic cell clearance www.biorxiv.org/content/10.6...
rupress.org/jcb/article/...
www.nature.com/articles/s41...
The p97 adaptor p47/NSFL1C is necessary for stress granule dissolution after heat stress www.biorxiv.org/content/10.6...
This study describes a new mechanistic framework for the initiation of primary cilium formation, based on the characterization of unique vesicular membrane intermediates at the mother centriole reveal...
In contrast to prevailing dogma, we report that procollagen 1 assembles into a liquid condensate within cells, resolving the long-standing problem of how c
rupress.org
Excess fatty acids can disrupt membrane and organelle function. Cells buffer fatty acid toxicity by synthesizing and storing triglycerides (TGs) in lipid droplets, but their capacity for TG storage is...
α5β1 and αvβ3 integrins are core components of focal adhesions (FAs) involved in cell attachment, migration, and mechanobiology-dependent processes. Recent works indicate that both integrins organize ...
The cryo-electron microscopy structure of the bridge-like lipid-transfer protein VPS13A
in complex with the scramblase XK—coupled with molecular dynamics simulations—suggests
that VPS13A-transported l...
www.cell.com
Beyond serving as cohesive barriers, epithelial tissues are involved in tissue surveillance and actively clear apoptotic cells to regulate development, tissue homeostasis and inflammation across speci...
Diao, Zou et al. demonstrate that activation of the integrated stress response drives lineage dedifferentiation and tumour progression in lung adenocarcinoma, associated with aberrant mitochondrial fu...
The global epidemic of myopia constitutes a growing public health concern worldwide.
Myopia development is characterized by pathological scleral re...
www.pnas.org
Centrosomes are cytoplasmic microtubule-nucleating structures. They are considered membraneless organelles, but in several cell types they are surrounded by ER-derived membrane. In C. elegans early em...
Stress granules form in response to diverse cellular perturbations to sequester translation components until the stress is resolved. Stress granules are composed of RNA-protein assemblies in membrane ...
