'Every two weeks we now generate more lead‑optimization structural data on #dengue than we did in the previous two decades combined. The pace of the ASAP open-source project is astounding,' said @griffen-ed.bsky.social, technical director @medchemica.com. (1/3)
🤔 Why are some medicines injectable, but others come as tablets? What are the challenges of manufacturing drugs for NTDs? Why is acoziborole white?
Dr Stephen Robinson, our Pharmaceutical Development Director, answers all these questions (& more) here👇
youtu.be/7KvGr_kux-E
MedChemica, Diamond, CMD & DNDi are partners in the ASAP consortium, an open-science project aimed at discovering & developing new medicines against viruses of pandemic potential, including coronaviruses & dengue virus.
More about ASAP: dndi.org/research-dev... (3/3)
‘Our partners @diamondlightsource.bsky.social & @cmd.ox.ac.uk are analyzing the molecular structures of around 10 new compounds most weeks. We still have a lot to do, but this is clearly the way to tackle dengue and deliver promising new drug candidates that we can advance to the clinic.' (2/3)
How does acoziborole kill sleeping sickness parasites? A fascinating deep dive into the chemistry behind our new medicine, its molecular structure and its distinctive feature: a boron-based scaffold called benzoxaborole.
By @chemistryworld.com www.chemistryworld.com/news/boron-p...
When Jaqueline was diagnosed with cutaneous #leishmaniasis at 10, she endured painful injections & walked 13k to receive treatment at the health unit.
We aim to develop an entirely new generation of all-oral medicines that make treatment easier for every patient.
youtube.com/shorts/g5c15...
Join us for a #dengue roundtable side event to explore:
🔬 Integrated surveillance and data-driven decision-making
💊 R&D for new diagnostics, vaccines, and treatments
🤝 Regional cooperation and equitable access to health technologies
Info & registration👉 community.pasteur-network.org/events/208484
Our statement at the 6th meeting of the Intergovernmental Working Group (IGWG) on the WHO Pandemic Agreement⤵️ dndi.org/statements/2...
"[Acoziborole] can dramatically simplify patient care, improve access to treatment and accelerate progress toward the elimination of sleeping sickness. It is a transformative tool," says Dr Priotto, @who.int.
Read more about our new treatment in @npr.org: www.npr.org/2026/03/16/g...
For too long, pregnant & breastfeeding women have been left out of clinical studies. The @britpharmsoc.bsky.social calls to:
👉 Include them when appropriate
👉 Strengthen safety & effectiveness data
👉 Give women clear & accessible information
🔗 bit.ly/4bKA6tW
Acoziborole is the first single-dose treatment for both early and late stage sleeping sickness
