What a nice way to end 2025: absence of caspase 8 in #sclc leads to neuronal-like reprogramming and promotes #metastasis via #necroptosis driven #inflammatory response. Congratulations to Ariadne and collaborateurs @unicologne.bsky.social @dtg-cologne.bsky.social !
www.nature.com/articles/s41...
Caspase 8 protein expression is largely absent in small cell lung cancer (SCLC) patients. Here, the authors generate a caspase 8 deletion SCLC mouse model and show that it promotes a neuronal progenit...
