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ICYMI: Extrafollicular plasma cells suppress T cell priming in tumour-draining lymph nodes
Extrafollicular plasma cells suppress T cell priming in tumour-draining lymph nodes
Nature Reviews Immunology, Published online: 08 June 2026; doi:10.1038/s41577-026-01321-2A preprint by Alberts et al. shows that extrafollicular plasma cells suppress dendritic cell activation and trafficking in tumour-draining lymph nodes, which results in failure to establish an antitumour memory T cell response in immune-cold, triple-negative breast cancer.
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Nature Reviews Immunology