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Cytokine receptors do not get old, my friends!
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GBM (Gesellschaft für Biochemie und Molekularbiologie)
Cytokine multimerization: when more is more and sometimes less
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Nature Reviews Immunology, Published online: 08 April 2026; doi:10.1038/s41577-026-01290-6This Review discusses how cytokine multimerization affects the engagement of cytokines with their receptors and their biological activity. The authors explain the relevance of cytokine multimerization in disease settings and the implications for cytokine-targeting therapies.
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Cytokine multimerization: when more is more and sometimes less
Nature Reviews Immunology