"Taken together, our results suggest that the genome-wide genetic architecture of gene expression involves fewer regulators for each gene but implicates the same regulators more often across genes (i.e., is less polygenic and more pleiotropic) than previously anticipated."
Aguirre et al. describe a model of gene regulatory networks and show how their properties
shape the distribution of genetic effects on gene expression. Their results imply
constraints on real network ...
