Just posted (bioRxiv): A novel #mechanobiology model revealing how #immune #Tcells combine a #nucleus as a #piston, an #uropod, and #microenvironment to power #amoeboid #cellmigration in #cellconfinement via a hydraulic cell engine. #CellBiophysics #ImmuneMigration
www.biorxiv.org/content/10.1...
Environments can induce cell structural instability, resulting in cell fragments shedding that can actively migrate, as described by as #Blebbisomes, or, as some decided to go more Hollywood with the terms, #Zombosomes.
Old, but gold. #Tcells often form tentacles to recognize their #antigens. And the resulting #lymphocyte's #immune #synapse is a dynamically unfolding spiral around #TCR microclusters. academic.oup.com/ib/article/7...