Happy to share our new preprint on BBB mechanobiology on bioRxiv:
www.biorxiv.org/cgi/content/...
We describe an exciting new link between tight junctions and cell-matrix adhesions during BBB maturation and in epileptic BBB dysfunction.
Brain endothelial cells (ECs) rely on mechanical cues to provide a physical barrier that protects the brain. Yet how ECs integrate forces to establish and maintain the blood-brain barrier (BBB) remain...