This is such a neat idea from the @narayanlab.bsky.social and the @hartwiggroup.bsky.social now in #JACSasap fooling enzymes with a removable binding ligand to accept non-native substrates #ChemSky
Enzymatic halogenation of C–H bonds is a promising approach to synthesize chlorine-containing compounds. However, few halogenases chlorinate C(sp3)–H bonds of molecules lacking a carrier protein, and ...
