She/her.
Doctoral researcher at MPI for Brain Research, in the lab of @erin-schuman.bsky.social.
Molecular Neuroscience. RNA biology and ribosomes. Local Translation. CRISPR systems.
Hyped about bioengineering and AI in biology.
Amateur illustrator.
Mara Mueller
Loading...
I’m happy to share that our paper about the Sepia officinalis genome is out in eLife!🧬 We compared the assemblies of two individuals that had a different predicted number of chromosomes, and found highly repetitive regions that likely prevented a complete assembly.
elifesciences.org/articles/107...
Ultrastructure of dopaminergic varicosities revealed by cryo-correlative light and electron microscopy. New study from Matthew Domenic Lycas (@lycasworks.bsky.social), Simon Erlendsson et al. @ucph.bsky.social:
rupress.org/jcb/article/...
#Neuroscience #Organelles #StructuralBiology #cryoCLEM
Ribosomes in pairs: A survival strategy inside stressed cells.
When nutrients drop or temperatures shift, cells switch to survival mode. New work by @erin-schuman.bsky.social & colleagues shows that inactive ribosomes pair up via a ribosomal RNA link @andschwarz.bsky.social @muellermara.bsky.social
Even more hibernating dimers out there!
A new preprint by @qiangguo.bsky.social shows oligomerization of inactive ribosomes is a mechanism shared across different expansion segments and stress conditions.
🎉 We’re delighted to announce Professor Erin Schuman, will become Director of the UCL Queen Square Institute (@uclqsion.bsky.social) from 1 Jan 2027.
www.ucl.ac.uk/news/2026/ap...
The peer reviewed version is out. Our study suggests this process is not limited to a single dimer architecture: we identified an additional dimeric arrangement, pointing to greater structural diversity in stress-induced ribosome hibernation-like states. doi.org/10.1093/nar/...
It is exciting to see closely related biology highlighted in a recent Science paper as well, underscoring the importance of this field. science.org/doi/10.1126/...
Our paper is now out in Science! Super excited to share our discovery that #mitochondria #pearling is the elusive mechanism driving the regular distribution and inheritance of #mtDNA nucleoids 🧬 [1/6]
Out now in @science.org
Ribosomal RNA expansion segments mediate the oligomerization of inactive animal ribosomes | Science www.science.org/doi/10.1126/...
Simone (she/her)
Journal of Cell Biology
Max Planck Institute for Brain Research
Mara Mueller
UCL Faculty of Brain Sciences
Stella Hurtley
Juan C. Landoni
Cells down-regulate protein synthesis when stressed to conserve energy and shift resources toward repair. We found that in some mammalian cells, including neurons, stress also resulted in the formatio...
Cells down-regulate protein synthesis when stressed to conserve energy and shift resources toward repair. We found that in some mammalian cells, including neurons, stress also resulted in the formatio...
Abstract. Inhibition of messenger RNA translation is a common feature in proteostatic stress cellular responses. Puromycin, a widely used compound for stud
doi.org
Excited to share our new study:
rRNA expansion segments are not passive structural elements — they mediate hibernating ribosome interfaces and reshape translation under stress. www.biorxiv.org/content/10.6...
The peer reviewed version is out. Our study suggests this process is not limited to a single dimer architecture: we identified an additional dimeric arrangement, pointing to greater structural diversity in stress-induced ribosome hibernation-like states. doi.org/10.1093/nar/...
Excited to share our new study:
rRNA expansion segments are not passive structural elements — they mediate hibernating ribosome interfaces and reshape translation under stress. www.biorxiv.org/content/10.6...
Abstract. Inhibition of messenger RNA translation is a common feature in proteostatic stress cellular responses. Puromycin, a widely used compound for stud
Excited to share our new study:
rRNA expansion segments are not passive structural elements — they mediate hibernating ribosome interfaces and reshape translation under stress. www.biorxiv.org/content/10.6...
