We study DNA topology, the action of topoisomerses and DNA break repair to understand genome organization, dynamics and stability @cniostopcancer.bsky.social
https://repairome.bioinfo.cnio.es
CortésLab
Congratulations to all the people involved, also in
Ana Losada's
@rfleiro.bsky.social
@gmaci.bsky.social
labs
@cniostopcancer.bsky.social
Specially leading authors
Ernesto López de Alba
@israelsalguero.bsky.social
Daniel Giménez Llorente
Very proud of you!!!
We provide:
- A catalog of how more than 18K genes affect DSB repair sequence outcomes induced by CRISPR-Cas9
- Examples of how it can be used at different levels, from identifying novel factors and functional relationships, to explaining mutational signatures in cancer
Kickstarting our Bluesky🦋 account with great news!
Our REPAIRome study finally out today in
@science.org
www.science.org/doi/10.1126/...
CortésLab
Check out our web tool to see interactive networks of DSB repair genes, browse your gene of interest for its contribution to DSB repair profiles and analyze functional relationships based on similarities in repair patterns
Enjoy!!!
repairome.bioinfo.cnio.es
Also: Research positions in the Ramsden lab. Post doctoral position - 5 years funding available. Cross-country collaborative, working closely with the groups of Gupta, Rothenberg, Wood, and Doublie.
Some example pubs from the last two post docs: PMIDs 37968395,35927262, 2963245, 30213916, 26240371
