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Scientist in North Carolina studying chromatin remodelers and transcription factors. @fnucleosome.bsky.social coorganizer ORCID: 0000-0002-6256-144X Views and posts are all my own
Jackson Hoffman









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The Thermo Fisher situation keeps getting worse. We've now collected 450+ problematic images presented as verification data in TF's antibody catalog. This includes: 🖌️ Dozens more images with duplications or painting 🖨️ Hundreds of blots that all share the same background (behold slideshow below)
We're starting in 45 minutes, register and join us to hear about the outstanding work Mark, Jake, and Sid are doing!
My Fragile Nucleosome seminar is now on YouTube www.youtube.com/watch?v=ksXp... I discuss our recent work showing that linker histone H1 behaves as a liquid-like glue for chromatin organization in living human cells 🧬 Paper: www.science.org/doi/full/10.... Huge thanks to @fnucleosome.bsky.social!
Reminder that the Local Organic Intelligence Model located in your skull runs quite inexpensively on snacks and caffeine arstechnica.com/ai/2026/06/a...
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Video
Some report burning through their whole monthly "AI credit" allotment in a single day.
arstechnica.com
YouTube video by Fragile Nucleosome
www.youtube.com
AI costs how much? GitHub Copilot users react to new usage-based pricing system.
Kazuhiro Maeshima
Reese Richardson
Jackson Hoffman
Excited to share the first pre-print from our lab!! Check it out here! www.biorxiv.org/content/10.6... We found that many RNA-binding proteins canonically understood to regulate RNA processing can also function like transcription factors and cofactors to directly regulate transcription.
John Scalzi
Kazuhiro Maeshima
I am very grateful and excited about this opportunity! Big thank you to our fantastic team who have made this possible and to many supportive mentors 🙏
We’ve recently been awarded a MIRA R35 and an R01 to study non-canonical roles and missense mutations of the Polycomb system in health, cancer, and neurodevelopmental disorders. We are seeking an animal tech with lab manager duties. Please share!