"mtDNA copy number and expression are largely decoupled, and above a certain rate-limiting threshold, mtDNA accessibility — rather than absolute copy number — is the more relevant quantity for explaining inter-individual differences in gene expression."
Mykhaylo M. Malakhov
Our preprint on the genetic regulation of mtDNA gene expression in collaboration with @shwetaramdas.bsky.social and @rajivmccoy.bsky.social .