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Androgens generally dampen anti-cancer immunity. A new study finds that in brain tumours they counteract a neural pathway that would otherwise suppress anti-tumour responses, making androgen signalling protective within the brain. 🧪 www.nature.com/articles/s41... and www.nature.com/articles/d41...
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Androgens have distinct roles in the brain, acting as immune-based tumour suppressors through neuroinflammation and neuroendocrine mechanisms.
www.nature.com
Androgen loss accelerates brain tumour growth via HPA axis activation - Nature
Francesca Cesari