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Julia R. Box et al. 5′ leader defects drive persistent HIV-1 viremia on long-term ART. Nature Communications (2026).
doi.org/10.1038/s414...
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Traces of HIV-1 RNA remain in the plasma despite years of antiretroviral therapy (ART), sometimes causing nonsupressible viremia (NSV). Here, the authors show that 5′Leader-defective RNA is the predom...
