IV vs PO GNB study
👩👨n=8,263 PO vs 901 IV 🦠Mostly E. coli; PsA 3.4% 💊PO: 47% FQs, 43% BLs (mostly CPD, no dosing)
📊Results ➡️ 90-day mortality: no difference
➡️ GNB recurrence: ⬆️ IV & ⬇️ PO, differed by PO group (Supp Tables A2 and A3)
academic.oup.com/ofid/article...
AbstractBackground. Step-down oral antibiotic therapy (SDO) is commonly used to treat uncomplicated gram-negative bacteremia (GNB), but real-world treatmen