And here it is: the final protocols for your future favorite 16S rRNA gene primer pair for anplicon sequencing studies -> V4EXT.
P.S. Mighty are the small ones - metric💩tons of Patescibacteria everywhere. Except in 💩, that is.
academic.oup.com/ismecommun/a...
Abstract. Primer bias in 16S rRNA gene amplicon sequencing can distort microbial diversity estimates by underrepresenting key taxa. We introduce a modified