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Excited to share this work from the Garcia Lab out today in @naturecomms.bsky.social! We engineer "cytokine adaptors", molecular immune switches that simultaneously block a target cytokine while inducing local activation of alternative cytokine receptors. rdcu.be/ec7GS
Mar 12, 2025
rdcu.be
Nature Communications - Cytokines are immune signaling molecules that are frequently dysregulated in disease. Here, the authors create engineered cytokine ‘adaptors,’ molecular switches...
Redirecting immune signaling with cytokine adaptors
Gita Abhiraman