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Immunologist - T cell biologist Opinions are my own https://kamphorstlab.org/ From Brazil, adopted by NYC
Kamphorst LAB









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Excited to head to Japan in November to present at the CSHA meeting on Immunoreceptor Signaling and Therapeutic Applications. Abstract deadline is next week! www.csh-asia.org?content/1343
Starting off the year with a glorious encounter between two Brazilian screen queens: Fernanda Montenegro, the unforgettable star of CENTRAL STATION, meets Kleber Mendonça Filho discovery Tânia Maria, a pistol in THE SECRET AGENT as Dona Sebastiana. Love this so much.
Hopefully a nudge in the right direction thehill.com/homenews/543...
🚀 NY-CURES Launch — Championing State-Wide Investment in Science! 🚀 Our new coalition advocates for sustained public support of New York’s vibrant biomedical research ecosystem — creating cures, economic gains & strengthening communities. Sign up. Stay informed. Join the movement: www.nycures.org/
BREAKING NEWS: a government watchdog confirmed the Trump administration is breaking the law by blocking NIH funds.   How many kids with cancer or grandmas with Alzheimer’s have to get closer to death while crucial research is stalled?  Trump must end this illegal funding freeze.
Thank you for the contribution of all co-authors! And the great review process at Immunity! urldefense.proofpoint.com/v2/url?u=htt...
9mo
5mo
10mo
9mo
Our paper is out! Check out this beautiful story where we uncovered that the costimulatory molecule ICOS is detrimental for PD-1+ CD8 T cells. Sustained ICOS signaling reduces memory-like features of progenitor exhausted CD8 T cells in chronic viral infection and liver cancer.
NY state friends, please do this today! The Governor’s State of the State is tomorrow, January 13 at 1:00 PM. We are hopeful she will announce the Empire Biomedical Research Institute (EBRI). Email the Governor and your Reps! actionnetwork.org/letters/supp...
10mo
These are extremely challenging times for early-career faculty. Here is my office's small contribution to make their hard and important work a bit easier: Download our curated and comprehensive database of funding opportunities for early-career faculty. Here: research.jhu.edu/rdt/funding-...
11mo
It was a privilege and a pleasure for both myself and @menezesnmaria.bsky.social‬ to preview a great upcoming article in @cp-immunity.bsky.social‬ by @kamphorstlab.bsky.social‬ showing an unexpected inhibitory role for ICOS in exhausted CD8+ T cells. www.cell.com/immunity/abs...
11mo
4mo
Mar 6, 2025
Kamphorst LAB
Kamphorst LAB
10mo
NY-CURES
Kamphorst LAB
Elizabeth Warren
David Rooney
www.csh-asia.org
WELCOME-Meetings-Cold Spring Harbor Asia
Kamphorst LAB
Kamphorst LAB
Tell New York Governor Hochul and your state legislators to support including the Empire Biomedical Research Institute in the 2027 Executive Budget. This is an urgent matter relating to funding life-s...
actionnetwork.org
Support the Empire Biomedical Research Institute (EBRI)
Understanding regulation of progenitor exhausted CD8+ T (Tpex) cell differentiation is important for immunotherapies. Humblin et al. report that sustained ICOS costimulation is detrimental to PD-1+CD8...
urldefense.proofpoint.com
The costimulatory molecule ICOS limits memory-like properties and function of exhausted PD-1+CD8+ T cells
Denis Wirtz
Ian Parish
A congressional watchdog determined Tuesday that the Trump administration broke the law when it directed the National Institutes of Health (NIH) to cancel hundreds of research grants earlier this y…
thehill.com
NIH broke law by withholding funding: GAO
📢 SIGN & SHARE THE PETITION! 📢 New York needs an Empire Biomedical Research Institute to create new statewide funding opportunities for scientists & physician-scientists so that patients and their families get the life-saving and life-changing new therapeutics they're hoping for ✏️ c.org/TDMy2H9JTW
Understanding regulation of progenitor exhausted CD8+ T (Tpex) cell differentiation is important for immunotherapies. Humblin et al. report that sustained ICOS costimulation is detrimental to PD-1+CD8...
urldefense.proofpoint.com
The costimulatory molecule ICOS limits memory-like properties and function of exhausted PD-1+CD8+ T cells
6mo
Support a New York State Biomedical Institute for a Healthier, More Affordable Future
c.org
ICOS agonists are being investigated for cancer immunotherapy based on the idea that they will reinvigorate exhausted CD8+ T cell anti-cancer immunity. Humblin et al. unexpectedly find the opposite—th...
www.cell.com
Sign the Petition
The high (I)COSt of costimulation for exhausted T cells
NY-CURES
The costimulatory molecule ICOS limits memory-like properties and function of exhausted PD-1+CD8+ T cells @cp-immunity.bsky.social @kamphorstlab.bsky.social www.cell.com/immunity/ful...
11mo
Waggoner Lab