New collaborative work from @crc1430.bsky.social now published in @natcomms.nature.com: Targeted degradation of #USP7 in solid cancer cells reveals distinct effects of deubiquitinase degraders and inhibitors.
➡️ www.nature.com/articles/s41...
DUBs regulate key cellular processes, but selective tools are scarce. Here, the authors developed PROTACs for the DUB USP7, comparing degraders with inhibitors. The study provides a valuable toolbox f...