New roles for lysosomes... and maybe new targets for Batten disease?
Loss of the lysosomal protein CLN3 triggers c-Abl-dependent YAP1 pro-apoptotic signaling | EMBO reports www.embopress.org/doi/full/10....
imageimageLoss of Batten disease-associated lysosomal protein CLN3 leads to DNA damage and activation
of c-Abl-YAP1-dependent pro-apoptotic signaling which underlies increased apoptosis
susceptibility...
