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Excited to share the 1st preprint from our incredible team at Interdict Bio as we progress novel, small-molecule sequence-selective inhibitors of translation toward the clinic to address difficult to treat cancers! #ribosome #interdictor Check out the preprint here: www.biorxiv.org/content/10.1...
Jan 22, 2025
Inhibitors of protein synthesis, including anisomycin, homoharringtonine, and other natural products bind in the peptidyl-transferase center (PTC) of the eukaryotic ribosome to inhibit translation. Re...
www.biorxiv.org
Context-dependent translation inhibition as a novel oncology therapeutic modality
Anthony Schuller