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I do bioinformatics stuff with @fulcrumgenomics.com. I do garden stuff at home in Somerville, MA.
Jess Smith







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Forget "geriatric millennial," I'll be introducing my generational status as the last person to be trained in mouth pipetting
17d
Very disappointed to learn from this paper that having good names for variable/functions/etc matters a lot to LLMs. That's the part I'm worst at! Hopefully my robot can pick good names for us arxiv.org/pdf/2510.03178
Seeing magma is a bucket-list item for me! So cool www.youtube.com/live/aI3bowg...
lol github.com/JuliusBrussee/caveman/
Jess Smith
Minibwa is a hybrid of bwa-mem and minimap2 and the successor of bwa-mem for short-read mapping. ~4X/2.5X as fast as bwa-mem/bwa-mem2 for WGS reads at comparable accuracy. Native support of directional bisulfite-seq. Applicable to long reads. Preprint at arxiv.org/abs/2606.15357
I like this! I'll certainly be sharing this guide to cold-emails with new grads and others looking to make a career change sriramk.com/coldemail
14d
17d
16d
2d
We talk a lot about therapeutic antibodies, but reagent antibodies are critical to so many fields of science. Shame! www.nature.com/articles/d41...
18d
Hot take: if our plan to save science rests on pharma CEOs....maybe we need a new plan www.biocentury.com/article/659615
🪨 why use many token when few token do trick — Claude Code skill that cuts 65% of tokens by talking like caveman - JuliusBrussee/caveman
github.com
17d
GitHub - JuliusBrussee/caveman: 🪨 why use many token when few token do trick — Claude Code skill that cuts 65% of tokens by talking like caveman
17d
Jess Smith
Jess Smith
Jess Smith