I do bioinformatics stuff with @fulcrumgenomics.com. I do garden stuff at home in Somerville, MA.
Jess Smith
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Forget "geriatric millennial," I'll be introducing my generational status as the last person to be trained in mouth pipetting
Very disappointed to learn from this paper that having good names for variable/functions/etc matters a lot to LLMs. That's the part I'm worst at! Hopefully my robot can pick good names for us
arxiv.org/pdf/2510.03178
Seeing magma is a bucket-list item for me! So cool
www.youtube.com/live/aI3bowg...
lol
github.com/JuliusBrussee/caveman/
Jess Smith
Minibwa is a hybrid of bwa-mem and minimap2 and the successor of bwa-mem for short-read mapping. ~4X/2.5X as fast as bwa-mem/bwa-mem2 for WGS reads at comparable accuracy. Native support of directional bisulfite-seq. Applicable to long reads. Preprint at arxiv.org/abs/2606.15357
I like this! I'll certainly be sharing this guide to cold-emails with new grads and others looking to make a career change
sriramk.com/coldemail
We talk a lot about therapeutic antibodies, but reagent antibodies are critical to so many fields of science. Shame!
www.nature.com/articles/d41...
Hot take: if our plan to save science rests on pharma CEOs....maybe we need a new plan
www.biocentury.com/article/659615
🪨 why use many token when few token do trick — Claude Code skill that cuts 65% of tokens by talking like caveman - JuliusBrussee/caveman