By combining widefield calcium imaging with EEG in mice, we find, consistent with previous work (pubmed.ncbi.nlm.nih.gov/40383825/), that stimulation triggers a CSD.
Crucially, the CSD perfectly predicts the expression of Fos, a key marker of neuronal plasticity.
Electroconvulsive therapy (ECT) is a fast-acting, highly effective, and safe treatment for medication-resistant depression. Historically, the clinical benefits of ECT have been attributed to generatin...