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New week, insights! ✨ The team led by Kinga Kamieniarz-Gdula (@stoplab.bsky.social) reveals in EMBO Reports how SETD2 acts as a genetic "traffic controller." A vital step in understanding cancer biology! Congrats to @michal-gdula.bsky.social, @agatakstepien.bsky.social, @mgkopczynska.bsky.social! 👏
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SETD2 is a methyltransferase responsible for depositing histone H3 lysine 36 trimethylation (H3K36me3). Loss of its enzymatic activity occurs in some cancers, including renal cell carcinoma. SETD2 mut...
SETD2 methyltransferase activity promotes correct transcription initiation and termination - EMBO Reports
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