Molecular machines, Proteostasis, Ubiquitin Signaling, Cell Autonomous Defense, Protein Disorders and Team Nematode
@IMP Vienna
www.imp.ac.at/groups/tim-clausen/
Clausen Lab
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Open Postdoc Position - Giant E3 ligases: mysterious mechanisms & non‑protein substrates. Interested? Join us to uncover how these molecular giants tag lipids, RNAs, sugars beyond proteins, on organelles and pathogens, to defend the cell. Details & Application here www.imp.ac.at/career/open-...
We offer a PostDoc position for a fully funded project on lipid-encoded #lipidtime protein quality-control checkpoints at the Golgi: great collaborators, excellent working & living conditions & benchspace with a view ;) Please share and repost!
Proud to share the yeast telomerase structure, led by the talented @hongmiaohu.bsky.social in collaboration with the Wellinger and Chartrand labs. Discovered 37 years ago and took us nearly 7 years but totally worth the wait 😍.
www.science.org/doi/10.1126/...
www.youtube.com/watch?v=gFE4...
Congratulations to Gautam Dey (EMBL) and Omaya Dudin (University of Geneva) for being awarded the EMBO Gold Medal 2026 in recognition of their outstanding contributions to the #LifeSciences in Europe! 🧪 https://www.embo.org/press-releases/embo-gold-medal-2026-awarded-to-gautam-dey-and-omaya-dudin/
Clausen Lab
Our paper is finally out! 🥳 If you want to know how a single Salmonella effector rewires the whole macrophage transcriptional landscape by hijacking one host transcription factor, check our latest research!
Thanks to the @thurstonlab.bsky.social and @peterwshill.bsky.social labs for an amazing work!
New study published in Science! Led by @thevirusmc.bsky.social and @plantophagy.bsky.social, former group leader at the GMI of the @oeaw.bsky.social, the researchers set out to understand how autophagy – the cell’s clean-up and recycling system – mediates plant immune response to viral infection.
😀
see also www.nature.com/articles/s41...
Structure-function analysis of the bacterial ClpE/ClpP AAA+ protease - Journal of Biological Chemistry www.jbc.org/article/S002...
"I would like to emphasize the importance of question-driven science...young scientists might enjoy science more if they are thinking about questions rather than just collecting data" journals.biologists.com/jcs/article/...
David Teis
Excited to share our work on the structure and function of cytoplasmic lattices within mouse embryos. A collaborative effort with @niakanlab.bsky.social and work led by @kashishsingh.bsky.social and @inaharasimov.bsky.social . It is now out on BioRxiv: www.biorxiv.org/content/10.6...
YouTube video by MRC Laboratory of Molecular Biology
www.youtube.com
The ability of Salmonella Typhimurium to exploit macrophages as a niche for survival, replication, and dissemination is central to its pathogenesis. T…
Noboru Mizushima is Professor of Biochemistry and Molecular Biology at the University of Tokyo, Japan, where he runs a laboratory studying the mechanisms and physiological functions of autophagy and o...
Cas12a2 enables RNA-triggered, sequence-specific killing of eukaryotic cells via widespread DNA shredding, allowing selective elimination of cells on the basis of gene expression, including virus-infe...
Gregor Mendel Institute of Molecular Plant Biology
Alexis Verger 🧬🧫🧪
Richard Sever
Led by Investigator Scientist @hongmiaohu.bsky.social, @kellythd-nguyen.bsky.social’s group in the LMB’s Structural Studies Division have produced the first ever structure of telomerase from yeast.
Read more here: mrclmb.ac.uk/news-events/...
#LMBResearch #cryoEM 🧪
Carter Lab
Video
New pre-print 📣 “Undruggable” cancer mutations remain very hard to target with current modalities. What if we could instead sense mutant transcripts and convert that recognition into selective cell killing?
Check out this work led by postdoc Jingkun Zeng:
www.biorxiv.org/content/10.6...
MRC Laboratory of Molecular Biology
www.biorxiv.org
Doudna Lab
General and regulatory proteolysis in bacteria is executed by a set of ATP-dependent
proteases composed of hexameric ring-forming AAA+ proteins and associated peptidase
barrels (e.g. ClpP). These AAA+...
