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Chronic inflammation has long been linked to cancer, but how is that history retained in the tissue? In a new #Nature study, Nagaraja et al show that colitis leaves a lasting epigenetic memory in colonic stem cells, which persists after inflammation resolves & primes for subsequent tumor growth 🧪🔬
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Chronic inflammation increases the risk of colon cancer. This inflammation drives epigenetic changes in the nucleus of stem cells that promote tumour formation.
www.nature.com
Remembrance of inflammations past
Johanna Joyce