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Dev bio, cell bio, stem cells, regen med, all things kidney. Punk rock and whisky enthusiast. Personal account and opinions. #firstgen
Lori O'Brien
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When your cat is obsessed with #PuppyBowl. As a special needs adoptee herself, she’s a huge advocate.
The beauty of the kidney arterial tree for this #FluorescenceFriday. Evans Blue dye labels the vasculature. Image courtesy of postdoc Sarah McLarnon.
For #FluorescenceFriday, an E10 embryo showing Pax2 localization. #DevelopmentalBiology
Happy to share scHiCAR, an ultra-high throughout (millions of cells), low cost (5 cents/cell including NGS), and trimodal platform for integrated single-cell level analysis of mRNA, open chromatin, and 5-kb resolution looping with ground-truth data the same individual cell.
4mo
4mo
I am very excited to visit NC State this weekend and give a seminar on Monday! I'll be in Raleigh from Saturday to Tuesday so I'm joyfully accepting all running trail suggestions, dining ideas, cool places to sit and write 6 R01s, and any friends who want to say Hi! gga.ncsu.edu/event/tim-mo...
1mo
3mo
Our first cancer biology preprint is up! TRIM9 switches melanoma cell phenotypes. First author @klukasik.bsky.social has taken the lab into new directions for sure in a fun collaboration with @coronin.bsky.social. We can't wait to hear what you think. www.biorxiv.org/content/10.6...
A blue Tulip (Sustentacular cell) behind some red (OMP) OSN cell bodies, and some green horizontal basal cells in the olfactory epithelium. Stylized for a science art presentation (easier to find than original).
4mo
2mo
3mo
An old favorite for this #FluorescenceFriday. This "rose" is actually a kidney glomerulus (red, podocytes) and an axon reaching towards it (green).
Lori O'Brien
Lori O'Brien
Lori O'Brien
3mo
Great things still happen all around us. Each your UNC Biology's Bob Goldstein and Art's Beth Grabowski co-teach ARTS/BIOL 409, that brings together artists and scientists to explore an intersection of two disciplines. It culminated this year with a remarkable show Friday 1/n
In @elife.bsky.social: A high-resolution, easy-to-build light-sheet microscope for subcellular imaging doi.org/10.7554/eLif...
5mo
Yarui Diao
4mo
Lori O'Brien
Stephanie Gupton
A high-resolution, easy-to-build light-sheet microscope for subcellular imaging
An accessible light-sheet microscope delivers subcellular-resolution, multicolor volumetric, and live-cell imaging, lowering barriers to state-of-the-art performance.
doi.org
I-75 Scientist
Mark Peifer (He, him)
Kevin Dean
Video
www.biorxiv.org
gga.ncsu.edu
Office of University Interdisciplinary Programs
Tim Mosca, Thomas Jefferson University
An old favorite for this #FluorescenceFriday. This "rose" is actually a kidney glomerulus (red, podocytes) and an axon reaching towards it (green).
3mo
Video
Lori O'Brien
Trimodal single-cell profiling of transcriptome, epigenome and 3D genome in complex tissues with scHiCAR - @yaruidiao.bsky.social @dukehealth.bsky.social go.nature.com/4rZqimf
3mo
Nature Biotechnology
Trimodal single-cell analysis reveals gene-regulatory architecture in complex tissues.
go.nature.com
Trimodal single-cell profiling of transcriptome, epigenome and 3D genome in complex tissues with scHiCAR - Nature Biotechnology
Tim Mosca (he/him)