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A recent @natneuro.nature.com paper analyzed lesion network mapping and raised concerns about the validity of the method. See below 👇 for our response. www.biorxiv.org/content/10.6...
3mo
Andreas Horn
A recent paper in @natureportfolio.nature.com raised concerns about the lesion network mapping method. Our team of 16 coauthors analyzed >1000 lesions and 34 symptoms and found that "The methodological foundations of lesion network mapping remain sound" www.biorxiv.org/content/10.6...
3mo
Grateful for the mentorship of @andreashorn.org and Garance Meyer, and for an incredible group of collaborators behind this work!
Renauld et al. present scilpy, an open-source #Python library for diffusion magnetic resonance imaging and tractography: doi.org/10.52294/001... @ohbmofficial.bsky.social
www.biorxiv.org
Thanks to The Transmitter for reaching out to me for comments on this methodological challenge to lesion network mapping. Scientific debate is critical to methodological advancement - so let the debate begin! www.thetransmitter.org/brain-imagin...
5mo
5mo
Michael Fox
4mo
The lesion network mapping method, used to identify disease-specific brain networks for clinical stimulation, produces a nearly identical network map for any given condition, according to a new study.
www.thetransmitter.org
Methodological flaw may upend network mapping tool
Lauren Hart
Aperture Neuro
Michael Fox
Konstantin Butenko compares four methods for mapping structural network activations in deep brain stimulation—two simple, two complex; some deterministic, some probabilistic—into @lead-dbs.org for direct use in the Fiber Filtering Explorer. See the methods paper below 👇👇
Massive, Herculanean work by @laurenahart.bsky.social and Garance Meyer to compile and integrate findings from DBS for epilepsy (20 targets!) including meta-analytical evidence for optimal stimulation sites for the two main targets (ANT & CM). Preprint out now 👇👇
9mo
11mo
A special thanks to my mentors over that few last years, @andreashorn.org and Garance Meyer. You’ve guided me through this project and helped shape the researcher I’m becoming. I’m incredibly grateful to have learned from you and to work alongside you.
Andreas Horn
Andreas Horn
🧠 ⚡️ Preprint alert ⚡️ 🧠 I️n the most comprehensive review of DBS in epilepsy, with 124 studies, 1,210 patients, and 20 anatomical targets we map where stimulation works best and why. Deep Brain Stimulation for Epilepsy: Optimal Targeting and Clinical Outcomes www.researchgate.net/publication/...