Professor of Structural Virology and Associate Director at the MRC-University of Glasgow Centre for Virus Research (CVR). Director of the Scottish Centre for Macromolecular Imaging. CryoEM, viruses, music, field archery, scicom and pix of our toy poodle.
David Bhella
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First time out in the woods at Palacerigg this year. Not too shabby groups, although my bow feels very heavy… will take a bit of practice before I shoot a round I think.
Wow - this is just amazing. Hui Guo and colleagues from John Briggs’ lab use cryoEM helical reconstruction to discover how filamentous influenza virion assembly is directed by multiple conformations of M1 - explaining how NA is concentrated at the proximal pole.
www.biorxiv.org/content/10.6...
How to get ahead in academia
1. Creative thinking.
French professor investigated for awarding himself fake prize www.bbc.co.uk/news/article...
Amazing work from Charlotte Lewis - our latest preprint describes structure guided development of an antiviral peptide, targeting VP2 portal assembly - a strategy that may have broad application to treat or prevent calicivirus disease.
www.biorxiv.org/content/10.6...
Delighted to share our latest preprint describing an integrative model for influenza A virions. We combined proteomics, lipidomics and cryo-ET to build a comprehensive set of models, using subtomogram averaging we show that IAV filaments package cofilactin. www.biorxiv.org/content/10.6...
Really happy to see this paper out now in PLOS Pathogens - a really nice collaboration with @alanlparker.bsky.social - led by Kasim Waraich and Rosie Mundy. journals.plos.org/plospathogen...
The abstract deadline for the 21st International Microscopy Congress has been extended to 20th March. Pranav Shah and I will be chairing a one-day session on “Imaging pathogen biology from structure to mechanism” and we would love to hear about your work! www.imc21.org.uk
🚨New pre-print!🚨
Because influenza virions are highly variable in form no single method can show their molecular architecture in detail. Here, we integrate multiple structural and compositional approaches to identify new features of these beautiful virus particles
www.biorxiv.org/content/10.6...
Cats: the ultimate pets and scientific heroes. 🐱
Studying feline viruses to identify innovative solutions to prevent human infections. #preprint by @cb99-lewis.bsky.social, @dbhella.bsky.social & team #microbiology
#preLight by @orestissavva.bsky.social: prelights.biologists.com/highlights/i...
France confines more than 1,700 people to cruise ship over suspected norovirus death
www.biorxiv.org
Cats: the ultimate pets and scientific heroes. Researchers are studying feline viruses to identify innovative solutions to prevent human infections
One elderly passenger on vessel docked in Bordeaux has died and about 50 people have symptoms, say officials
French authorities have confined more than 1,700 passengers and crew members on a cruise ship docked in Bordeaux after a passenger died from suspected norovirus, officials have said.
The Ambassador Cruise Line vessel carrying 1,233 passengers, most of them British or Irish, arrived in Bordeaux on Tuesday. One 90-year-old passenger had died and about 50 people had shown symptoms of the virus, French health officials said. Continue reading...
Author summary Adenoviruses cause infections with pathologies ranging from cold like respiratory symptoms to gastroenteritis and conjunctivitis. In addition to research on adenovirus pathology, substa...
