3/10 LRP1 500-kDa soluble subunit (α) has four ligand-binding cysteine-rich complement type repeats (CRs) clusters (I to IV), with 31 CRs in total target different ligands, such as amyloid-β (Aβ), tau, receptor-associated protein (RAP), alpha-2-macroglobulin (A2M), and apolipoprotein E (ApoE)
Alt: The Dude Stirring His Drink wondering about how LPR1 can bind so many different ligands!