Bacterial cell division protein FtsZ complexes with a phage protein to activate bacterial immunity
@natmicrobiol.nature.com from Michael Laub & Abel Garcia-Pino
www.nature.com/articles/s41...
The CRISPR-Cas system in E. coli K-12 is considered inactive.
We questioned whether mobile elements encode anti-CRISPRs against this system and found a highly abundant AcrIE9-AcrIE10 tandem and a novel AcrIE13 — an HTH protein more similar to Aca than known Acrs.
www.pnas.org/doi/10.1073/...
🎊 New Preprint from phagefoundry.org ! Super excited to share our latest work on generating systematic phage-MDR P. aeruginosa interaction dataset & use of ML to predict phage susceptibility & phage cocktails from target genome sequences alone, w validations www.biorxiv.org/cgi/content/...
New online! Revisiting the life cycle of temperate phages
Some gut commensals are not what they look like.
E. coli HS borrows a capsule from Klebsiella, boosting its phage resistance.
We also uncovered tail-spike exchanges between phages of different morphotypes and a P22 with dual TSP architecture.
www.biorxiv.org/content/10.6...
TIR-like NADases act in bacterial immunity and the RNA vault https://www.biorxiv.org/content/10.64898/2026.05.01.722283v1
Congrats to Zhang et al. on our preprint describing a large-scale genomic inversion of Eggerthella lenta involving CPS gene clusters, enabling bacteriophage evasion. Collaboration between UCSF and @ucc.ie with @apcmicrobiomeirel.bsky.social DOI: doi.org/10.64898/202... #phage #gut #evasion