Cool to see this! content.govdelivery.com/accounts/US...
And I'm thrilled to be betting on Katharine's vision here! As a grad student, she co-invented the R21 malaria vaccine that's now reaching millions of kids. I'm hoping to see hundreds of millions of future Strep A vaccine doses with her fingerprints on them.
Great to see GiveWell CEO Elie Hassenfeld on the TIME100 Philanthropy list, well chosen! time.com/collection/...
Our goal is to double the number of Strep A vaccine candidates in clinical trials and have at least one ready for Phase 3 trials by the end of 2030.
→ A huge problem: ~1% of total annual deaths worldwide (>600k)
→ Super neglected: ~$14M/yr of R&D globally before this, ~50x less than malaria which has similar mortality
→ Newly tractable: new human challenge models and earlier diagnostics should speed the path to an approved vaccine