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Cell aims to publish the most exciting and provocative research in biology. Posts by Scientific Editors on the Cell editorial team. See the latest papers at https://www.cell.com/cell/

This amazing work by @danialv.bsky.social and Bodan Hu is now out in peer-reviewed form at @cp-cell.bsky.social with a lot of new simulations! Check it out if interested in lipid transport!

Happy to finally share the amazing results of our long-term collaboration with Karin Reinisch’s lab on how bridge lipid-transfer proteins (BLTPs) cooperate with partner proteins to orchestrate lipid delivery. A quick thread (1/7) www.biorxiv.org/content/10.6...

Single intracerebroventricular CAR T cell dose in patients with recurrent glioblastoma induces dose-dependent endogenous immune remodeling. Cytotoxic NK cell expansion is associated with prolonged survival, whereas Treg expansion and baseline scavenger myeloid cells are associated with poor outcomes.

Nuclear and cytoplasmic proteomics uncover a nuclear pool of cytoskeletal proteins, including MAP1B, whose shuttling to the nucleus increases BRG1/BAF chromatin association and regulates brain development.

Live imaging covering the entire human pre-implantation development reveals that the second mitotic division is the most error-prone, where stochastic centriole overduplication predisposes 2-cell embryos to missegregating chromosomes and arresting before the 8-cell stage. By contrast, later embryonic arrest involves endoplasmic reticulum stress.

The cryo-electron microscopy structure of the bridge-like lipid-transfer protein VPS13A in complex with the scramblase XK—coupled with molecular dynamics simulations—suggests that VPS13A-transported lipids are delivered from the protein directly to the membrane, near to the scramblase that equilibrates lipids between the membrane’s leaflets as new lipids arrive.

Gregory J. Hannon passed away in April 2026 at the age of 61. A towering figure in modern molecular biology, Greg influenced remarkably diverse areas of science. His work reshaped our understanding of gene regulation, advanced the discovery of tumor suppressors that regulate the cell-cycle machinery, and uncovered fundamental mechanisms of RNA interference. By establishing core principles of small RNA biology, he not only transformed our mechanistic view of RNA-silencing pathways but also pioneered functional genomics approaches that revolutionized basic and biomedical research in mammalian systems.

Complete biosynthetic pathways for cephalotaxinone and homoerythratine were elucidated from the endangered plant Cephalotaxus fortunei. Thirteen key enzymes were identified, including two homologous cytochrome P450 enzymes that catalyze a rare divergent oxidation process governing alkaloid scaffold diversification. Full pathway reconstitution in Nicotiana benthamiana establishes a foundation for the sustainable production of the anticancer agent homoharringtonine.