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Transposons, chromatin, development. Group leader @ the MRC LMS in London and UKRI FLF. Mum of 2, she/her. Www.perchardelab.com
Michelle Percharde









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Very excited to be part of this prestigious programme, thank you @embo.org !
🚨Our story is published! Same bones but + dissection of MERVL’s role integrating signals from #ZGA factors, & + about pathological DUX4 activation of NOXA #TEsky. Thanks to all revs for their helpful comments improving the ms. Even #rev3 - until they ghosted us 😜 www.science.org/doi/epdf/10....
6mo
#TEsky
🚨Post open in our lab! Come work on some cool themes involving metabolism, chromatin, early development 🤓. Pls RT
Congratulations to the new cohort of 28 EMBO Young Investigators! They are joining an international network of more than 800 life scientists – Welcome! Read the press release here: https://www.embo.org/press-releases/twenty-eight-group-leaders-become-embo-young-investigators/
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New preprint from the lab! We dig into the regulatory roles of TEs in the mouse placenta, with some surprising findings. Led by the awesome @smamante.bsky.social. Particular kudos to him for navigating the many twists and turns of the project.
Michelle Percharde
We are excited to be recruiting a new tenure track group leader in the Structural Studies Division at MRC LMB! It is an amazing place to start your own lab. @mrclmb.bsky.social Please get in touch if you have any questions. www.nature.com/naturecareer...
Michelle Percharde
www.cell.com/molecular-ce... check this beautiful paper
Michelle Percharde
4mo
Michelle Percharde
EMBO
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Register now for our one-day symposium at the MRC Laboratory of Medical Sciences on environmental and metabolic control of early development on 4 December 2025! Spaces are limited, register here: www.symposia.org.uk/courses/stem...
📣 We’re hiring 6 new Team Science postdocs! Our Team Science approach brings together interdisciplinary researchers to tackle questions no single field can solve alone. Find out more and download our brochure below
7mo
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Research Group Leader Tenure Track Starting Salary £67,979 to £76,868 per annum MRC Laboratory of Molecular Biology, Cambridge, UK The MRC Laborato...
Research Group Leader Tenure Track - Structural Studies - LMB 2775 - Cambridge, Cambridgeshire (GB) job with MRC Laboratory of Molecular Biology (LMB) | 12854636
www.nature.com
Team Science Project
lms.mrc.ac.uk
MRC Postdoctoral Research Scientists x 6 - MRC Laboratory of Medical Sciences
Miguel Branco
Lori Passmore
MRC Laboratory of Medical Sciences
MRC Laboratory of Medical Sciences
www.biorxiv.org
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www.science.org
CRISPRa-mediated disentanglement of the Dux-MERVL axis in the 2C-like state, totipotency, and cell death
Happy to share our first #bluetorial & our latest #preprint, lead by postdoc @paulchammas.bsky.social. We used CRISPRa to disentangle the close relationship between Dux and MERVL elements in the induction of the 2-cell like state: #TEsky #MERVL www.biorxiv.org/content/10.1... (1/8)
Congratulations to LMS group head @mpercharde.bsky.social who has been selected as one of this year’s EMBO Young Investigators! 🌟 The prestigious EMBO Young Investigator Programme supports exceptionally talented life scientists who represent innovation and excellence in their fields. @embo.org
Nov 26, 2024
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Join @mpercharde.bsky.social Lab at the MRC LMS! We have an 18mo postdoc position to cover a couple of projects (maternity leave and paper revisions). The projects are focussed on chromatin in early mouse embryos and metabolism in mouse embryonic stem cells and pluripotency.