Delighted our work on the development of a prime editing screening platform in HAP1 is now published in Cell Genomics. This was led by Christina Kajba and Michael Herger, who did very well to optimise all aspects. (Preprint thread: x.com/TheGenomeLab...)
www.cell.com/cell-genomic...
Herger and Kajba et al. introduce a prime editing platform to screen genetic variants
for functional effects in haploid human cells. Negative and positive selection screens
identify loss-of-function v...
