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Really enjoyed writing up this article with Lavonna Mark for @cp-trendscognsci.bsky.social on how internal states - like attention, arousal, or goals - can reshape our brain's map of space, helping the brain adapt navigation to what matters most. www.sciencedirect.com/science/arti...
3mo
Fun afternoon with the lab learning how to make homemade pasta!
New preprint! Circuit wiring isn’t just anatomy, it shapes computation. Disrupting CA1→subiculum topography reorganizes spatial coding and destabilizes network dynamics. Great collab led by Yanjun Sun, & with D Pederick, X Xu & L Lou! www.biorxiv.org/content/10.6...
Congrats @emilyaeryjones.bsky.social and team! The brain doesn’t just map where you are, it maps where it matters. Great thread below!
Anyone else running into NPX 2.0 supply issues? Heard there’s a 90 pause on accepting new orders 🫣
Lisa Giocomo
Beautiful early morning run yesterday from Chevy Chase to DC! Now time for science!
3mo
2mo
4mo
2mo
Sunrise run in NYC @rockefeller.edu
New paper! Congrats to @markplitt.bsky.social, Konstantin and team! The brain’s spatial map isn’t static but for hippocampus CA1 maps to change with experience, they need postsynaptic membrane fusion. A new link between synaptic machinery and flexible coding! www.sciencedirect.com/science/arti...
1mo
5mo
2mo
Great papers in spatial neuro this week. Csicsvari's group: hippocampal place fields stabilise during learning while mPFC stays flexible. Giocomo's lab: CA1-subiculum topography actively shapes boundary coding & corner cells. doi.org/10.64898/2026.03.27.714523 doi.org/10.64898/2026.03.24.714092
Lisa Giocomo
Lisa Giocomo
Lisa Giocomo
Lisa Giocomo
2mo
Rapid delivery of glutamate receptors to the postsynaptic membrane via vesicle fusion is a central component of synaptic plasticity. However, it is un…
www.sciencedirect.com
Hippocampal place code plasticity in CA1 requires postsynaptic membrane fusion
Lisa Giocomo
Lisa Giocomo
Lisa Giocomo
Spatial navigation in preclinical Alzheimer's disease: A review New review from @antoinegc.bsky.social and @antoinecoutrot.bsky.social labs, on which I am a co-author, and first author is the amazing Syrine Salouhou arxiv.org/abs/2603.23082
2mo
Caswell Barry
Hugo Spiers
Internal behavioral states influence many brain circuits, with well-known effects in sensory areas. Less is known about how these states shape downstr…
State-dependent spatial maps for navigation
www.sciencedirect.com