Now published as version of record at @elife.bsky.social !
Layers of Immunity: Deconstructing the Drosophila effector response. The tools are now deposited in the VDRC (link ⬇️)
elifesciences.org/articles/107...
shop.vbc.ac.at/vdrc_store/d...
#Drosophila #IDsky #SymbioSky #Infection #Immunology
Mark A. Hanson
Excited to finally announce this work which has been in the pipeline for 5 years: Layers of Immunity.
Faustine et al. made a set of immune mutants covering 4 major immune modules in #Drosophila, deleting melanization (ROS), phagocytosis, and both Toll & Imd NF-kB responses. What did we find?
1/n 🧵
www.biorxiv.org
The host innate immune response relies on the cooperation of multiple defense modules. In insects and other arthropods, which have only innate immune mechanisms, four main immune-specific modules cont...
