Antibiotics for chronic low back pain with disc herniation? This RCT says no. Amoxicillin-clavulanate for 90 days did not reduce pain vs placebo at 12 months—even in those with Modic changes. Avoid inappropriate antibiotic use. doi.org/10.1001/jama...
This randomized clinical trial examines whether amoxicillin-clavulanate is effective in a subgroup of individuals who have chronic low back pain with disc herniation and bone changes detected on…
