Our team of researchers at GeorgiaTech investigate mechanisms and consequences of microbial community dynamics both in the environment and during infection. https://sites.gatech.edu/cmdi/
Center for Microbial Dynamics and Infection
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Insects in hospitals are potential disease vectors! 🪳🪰
A new systematic review shows that cockroaches, flies, and ants often carry drug-resistant bacteria and can transmit pathogens to patients. 🏥
pubmed.ncbi.nlm.nih.gov/41562025/
#InfectionPrevention #PublicHealth #Microbiology
Arthropods in healthcare environments commonly harbor clinically relevant and antimicrobial-resistant microbes, and limited but compelling evidence supports their potential role in patient transmission. Strengthened pest management and environmental hygiene are essential components of infection prev …
Metabolomics ID's targets against the Burkholderia biothreat by finding metabolic shifts during infection. 🦠💊
pubmed.ncbi.nlm.nih.gov/41170848/
Studies of clinical isolates show that P. aeruginosa and S. aureus interact in strain-specific ways. Surprisingly, competition doesn't always rely on usual chemical signals (AQs), highlighting the complexity of infections.
pubmed.ncbi.nlm.nih.gov/41533460/
#Microbiology #Biofilms #HealthScience
Vibrio cholerae builds its protective biofilm using GluP. This glutamate-binding protein is key to maintaining biofilm architecture and coordinating growth/nutrient acquisition. Blocking GluP could disrupt transmission! #Microbiology #PNAS www.pnas.org/doi/10.1073/...
Extreme drought makes peatlands lose carbon much faster, and this loss is worsened by both warming and elevated CO₂. Climate change will significantly amplify carbon emissions from peatlands in the future. 🌡️🔥 #ClimateChange #Peatlands #CarbonCycle
pubmed.ncbi.nlm.nih.gov/41129626/
Researchers have sequenced the draft genomes of two Halobacteriovorax strains (GFR7 & GFR8) from Florida's Apalachicola Bay, advancing our look at these unique marine predators.
pubmed.ncbi.nlm.nih.gov/41427715/
#microbiology #genomics #science
R-pyocins, phage tail-like complexes, act as highly specific weapons against susceptible strains. Their non-replicative and potent nature makes them a prime candidate for next-generation antimicrobials against drug-resistant infections! #Microbiology www.microbiologyresearch.org/content/jour...
A bacterial predator, Halobacteriovorax, acts as a living "probiotic" that halts Vibrio-induced disease progression in endangered Caribbean corals. This shows microbial predators are promising new tools for coral disease therapy! #CoralReefs #MicrobialEcology #ISMEJ academic.oup.com/ismej/advanc...
A novel dual-fluorescence reporter to reveal how the sRNA Teg41 regulates virulence toxin production in Staphylococcus aureus strains. 🦠🔬 #AntibioticResistance #Pathogen #sRNA pubmed.ncbi.nlm.nih.gov/41170992/
The constant battle between bacterial immune systems (CRISPR) and MGEs is a critical, yet understudied, driver of microbiome structure & function. The paper calls for moving beyond simple models to understand these complex community-level interactions. #Microbiology journals.plos.org/plosbiology/...
<span><i>Burkholderia pseudomallei,</i> a gram-negative saprophyte that causes melioidosis, has been classified as a potential bioweapon, posing a serious global threat. Metabolic re-wiring, production of virulence effectors, evasion/suppression of host defenses, and modification of host cell functions co</span> …
<span><b>Introduction.</b> Chronic wounds are notoriously difficult to treat and are associated with decreased limb function, reduced quality of life and significant morbidity. Their recurrent nature, despite aggressive antibiotic therapy, is due in part to the presence of polymicrobial biofilms. <i>Pseud</i></span> …
pubmed.ncbi.nlm.nih.gov
Proceedings of the National Academy of Sciences (PNAS), a peer reviewed journal of the National Academy of Sciences (NAS) - an authoritative source of high-impact, original research that broadly spans...
Extreme drought events are predicted to increase with climate change, yet their impacts on ecosystem carbon dynamics under warming and elevated carbon dioxide (eCO<sub>2</sub>) remain unclear. In a peatland experiment with five warming treatments each under ambient carbon dioxide (aCO<sub>2</sub>) a …
Predatory bacteria are common in aquatic environments and associated with eukaryotic hosts. Here, we report draft genome sequences for two marine isolates, <i>Halobacteriovorax</i> sp. strains GFR7 and GFR8, that were isolated from Dickerson Bay in Apalachicola Bay, Florida, USA.
R-pyocins are phage tail-like protein complexes produced by Pseudomonas aeruginosa that deliver a single, lethal hit by depolarizing the target cell membrane. Unlike phages, R-pyocins lack capsids and...
Abstract. Predation is a top-down regulator of ecosystem integrity and a key driver of community structure and evolution in plants and animals. Despite our
<span><i>Staphylococcus aureus</i> is a common commensal of human skin and anterior nares but also a notable pathogen, causing a range of diseases from minor skin infections to serious, often fatal conditions. The global health community considers <i>S. aureus</i> a serious threat due to the rise of multi</span> …
Bacterial immune systems have evolved in response to diverse molecular "parasites", yet their ecological roles remain poorly understood. This Essay explores how interactions between mobile genetic ele...
