👉 An antidepressant inhibits the ABC transporter BmrA:
pubmed.ncbi.nlm.nih.gov/42252745/
Die potenziellen Nebenwirkungen von Clomipramin heben den Wert bakterieller Modelle für die Untersuchung neuartiger Inhibitoren hervor, wenn Studien am Menschen nicht durchführbar sind!
#SubtiWiki
Drug uptake is constrained by epithelial barriers, such as the intestine and the blood-brain barrier, which express efflux pumps such as the ABC-transporter ABCB1. Therefore, drugs targeting the centr...
