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We are thrilled to share our first preprint on ChemRxiv! Together with @morandilab.bsky.social, we applied nitrogen atom insertion to Trp-containing peptides for late-stage modification. A big thanks to Ann-Sophie, Eva, Masota, and Florin for their outstanding contributions! doi.org/10.26434/che...
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Peptide drugs are a powerful modality in modern drug dis-covery. Synthetic methods that enable the late-stage diversifi-cation of native peptides through amino acid-specific modifi-cations are thus in...
Late-Stage Diversification of Native Tryptophan-containing Peptides and Peptide Drugs through Nitrogen Atom Insertion
Nathalie M. Grob