New paper from the lab! www.cell.com/cell-reports...
@gmestrallet.bsky.social
@sinaiimmuno.bsky.social
Mestrallet et al. show that T cell-myeloid interactions determine response to PD-1
blockade in colorectal cancer. Targeting TREM2 macrophages together with LAG3, CTLA4,
and PD-1 reprograms the tumor m...
Glad to share our work about resistance to immunotherapy! We discovered a combination therapy allowing to eliminate CRC tumors. We also identified the T cell and macrophage subsets mediating the response. Thanks to the team! www.cell.com/cell-reports...
Plus, a small cartoon summarizing the study.
