Biochemistry PhD student in the Coyle Lab @ UW-Madison | Cornell & ZJU ‘19 | Protist lover & Science enthusiast
Zhejing (Maggie) Xu
Watching reaction-diffusion signaling couple to protein condensations feels like opening a new world of exotic subcellular spatial patterning 🌌 huge thanks to the evolving idea started from @edenchang.bsky.social and @cellraiser.bsky.social that make this journey possible and incredibly fun!
How did animal senses evolve? Max Coyle et al. used choanoflagellates to uncover TRPW, ancient ion channels predating animal somatosensory receptors. TRPW links microbial prey ecology to evolution of receptor structure, sensory organelles, & multicellular processing.
www.biorxiv.org/content/10.6...
Join us for Rohith Rajasekaran's (@born2raisecell.bsky.social) PhD thesis defense on Friday, Nov. 21! Rajasekaran's research was completed in the Coyle Lab (@cellraiser.bsky.social). More info: today.wisc.edu/events/view/...
Still get goosebumps thinking about @dudinlab.bsky.social’s presentation on the “microbial art gallery” at the GRC conference 🎇. So grateful for you and Marine 🪄 for helping us grow the suctorian corner of #ProtistsOnSky 💪
Thrilled to share our work on the 🔥 single-celled predator Podophrya collini, which rewires its cell morphology to hunt more efficiently. Huge thanks to our amazing team—Amy, Lauren, Omaya, Marine, Mari, and especially Scott—for making this shine! ✨
Zhejing (Maggie) Xu
Excited to share a new preprint! Wireless devices use FM modulation to transmit multiplexed noise-resistant data. Led by @born2raisecell.bsky.social, we create a biochemical analogue of this paradigm using genetically encoded oscillators (GEOs) for single-cell FM streaming tinyurl.com/nbs8rw42 🧵
Nicholas Bellono
Zhejing (Maggie) Xu
Zhejing (Maggie) Xu
UW–Madison Department of Biochemistry
Sub-cellular architectures arise through integrating signaling and structure. @edenchang.bsky.social and @zjmaggiexu.bsky.social show how coupling reaction-diffusion signaling to protein condensation provides a tunable, regulatable landscape for sub-cellular structure www.biorxiv.org/content/10.6...
Excited to share our new bioRxiv preprint!
We introduce RIPPLE, a synthetic platform that couples reaction–diffusion signaling with protein condensation to generate tunable intracellular architectures.
Grateful to @zjmaggiexu.bsky.social and @cellraiser.bsky.social. It’s been a rewarding journey.
Sub-cellular architectures arise through integrating signaling and structure. @edenchang.bsky.social and @zjmaggiexu.bsky.social show how coupling reaction-diffusion signaling to protein condensation provides a tunable, regulatable landscape for sub-cellular structure www.biorxiv.org/content/10.6...
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Scott Coyle
Very happy to see this out there ! Amazing work by @zjmaggiexu.bsky.social @amyweeks.bsky.social & @cellraiser.bsky.social!
All #ProtistsOnSky are amazing, but when I bumbed into @zjmaggiexu.bsky.social & her poster 2y ago at a #GRC conference, I got the urge to attempt #ExpnasionMicroscopy!
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How do cells adapt morphology to function? In a 🔥 preprint by @zjmaggiexu.bsky.social , with @dudinlab.bsky.social and @amyweeks.bsky.social , we identify a self-organizing single-cell morphology circuit that optimizes the feeding trap structure of the suctorian P. collini. 🧵 tinyurl.com/4k8nv926
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Omaya Dudin 𓂆 ¦🍉¦🦠¦🔬¦
Scott Coyle
How do cells adapt morphology to function? In a 🔥 preprint by @zjmaggiexu.bsky.social , with @dudinlab.bsky.social and @amyweeks.bsky.social , we identify a self-organizing single-cell morphology circuit that optimizes the feeding trap structure of the suctorian P. collini. 🧵 tinyurl.com/4k8nv926
