New paper in collaboration with the Förstemann Lab & Boekhoven Lab is out! Combining #NMR & mutational analysis, we characterize the unique features of the #Ago2 IDR region which drives Ago2/RNA #condensate formation.
doi.org/10.1093/nar/...
@clarahipp.bsky.social
Abstract. Biogenesis of small interfering RNAs (siRNA) in Drosophila melanogaster involves the processing of double-stranded RNA (dsRNA) by Dcr-2 with Loqs