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by @jimpick.com
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New paper in collaboration with the Förstemann Lab & Boekhoven Lab is out! Combining #NMR & mutational analysis, we characterize the unique features of the #Ago2 IDR region which drives Ago2/RNA #condensate formation. doi.org/10.1093/nar/... @clarahipp.bsky.social
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Abstract. Biogenesis of small interfering RNAs (siRNA) in Drosophila melanogaster involves the processing of double-stranded RNA (dsRNA) by Dcr-2 with Loqs
academic.oup.com
Molecular mechanisms of biomolecular condensate formation in Drosophila melanogaster siRNA biogenesis
Sattler Lab