Spatial Organisation of Signalling lab head, Associate Professor, Deputy Theme Leader @MIPS_DDB, pharmacology/cell signalling
Dr Michelle L Halls
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This is the result of a fantastic collaboration with @drellisdon.bsky.social at @monashuniversity.bsky.social, including first authors @luptoncj.bsky.social and @charlesbj.bsky.social, and co-lead Yong-Gang (Tyler) Chang. Special mention to Jade Dong and Terrance Lam from my team.
🏅 Lab Olympics 2025:
From a fun idea to a real tradition, this year we’ve hit a record 6 teams in the winter marquee at MIPS! Science is serious, but these moments of connection, laughter, and (slightly) fierce competition keep us going. Here’s to teamwork and the coveted winner’s button!
You can find out more here: www.cell.com/cell/fulltex...
The latest research from our team is out in Cell @cp-cell.bsky.social! We used #cryo-EM, #imaging, #BRET, and #biosensors targeted to the lysosome to understand how the KICSTOR-GATOR1 complex turns off #mTORC1 in response to low levels of amino acids.
Our latest paper from @monashuniversity.bsky.social Monash Institute of Pharmaceutical Sciences led by #PhD student Terrance Lam is out in Science Signaling today. We investigated how #GPCR #signalling can accelerate invasion in TNBC.
🔉 Only a few days left to vote! 🔉
Our 2nd CCeMMP Annual Bench to Art Competition gallery is LIVE! 🤩
ccemmp.org/events/arc-c...
Vote, like and repost :)
#membraneproteins
#scicomm
#nationalscienceweek
#cryoEM
#cryoET
Now online! Structure of the lysosomal KICSTOR-GATOR1-SAMTOR nutrient-sensing supercomplex
New work in #ScienceSignaling may answer why some patients with triple-negative breast cancer who receive beta-blockers have a lower risk of metastasis and identifies a factor that holds promise as a prognostic and therapeutic target. https://scim.ag/45XmD0b