Beautiful work by @kkjimbsky.bsky.social in collaboration with @nvastenhouw.bsky.social @pengellab.bsky.social where we used CRISPRi-seq in a zebrafish meningitis model of pneumococcal infection coupled with metabolomics. #MicroSky www.biorxiv.org/content/10.1...
Streptococcus pneumoniae is an important human pathogen that causes invasive diseases and remains the leading cause of bacterial meningitis. However, the bacterial determinants required for survival w...